Normal Foundations of Nutrition & Bioenergetics

CPR APPLICATIONS FOUNDATION · CHAPTER 14 · NORMAL

Normal Foundations of Nutrition & Bioenergetics

Organize the chapter before drilling into individual CPR concepts.

Supplemental foundation map: this page orients the detailed CPR Applications for Chapter 14. It is not part of the canonical CPR object inventory.

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14.1 · SOURCE CPR FOUNDATION

Concept

Nutrition and bioenergetics connect what enters the body to how the body stores, burns, repairs, and compensates. Step 1 rarely tests nutrition as diet trivia. It tests symptom clusters that trace back to a missing substrate, failed absorption pathway, or failed fuel switch.

Pattern

Step 1 usually gives the output failure first: bleeding, rash, neuropathy, anemia, edema, fasting intolerance, or mental-status change. The task is to reverse-map that output to a nutrient class, absorption problem, metabolic state, or treatment complication.

Rule

  1. Start with the pattern, then identify the missing input. Skin, blood, nerves, bone, and clotting findings each point toward specific nutrient groups.
  2. Separate deficiency from fuel-state failure. A patient who crashes during fasting has a different problem than one with a chronic vitamin-deficiency pattern.
  3. Watch for treatment-created physiology. Refeeding and glucose administration can worsen a vulnerable metabolic state.

Applications

  • Night blindness xerosis → vitamin A deficiency
  • Bleeding with prolonged PT/INR and normal platelet count → consider vitamin K deficiency among other causes, including warfarin exposure and liver disease
  • Macrocytic anemia neurologic findings → B12 deficiency
  • Dermatitis diarrhea dementia → niacin deficiency
  • Poor wound healing perifollicular hemorrhage → vitamin C deficiency
  • Neuromuscular, cardiac, or mental-status deterioration after nutrition restart → evaluate for refeeding-related electrolyte shifts, especially hypophosphatemia
  • Tip: Pattern first missing input second

CPR APPLICATIONS · ACTIVE REASONING

Infer the missing nutrient or fuel

Make a prediction first. Each worked answer is available without JavaScript. These exercises do not save or send responses.

Decision 1: Night blindness and xerophthalmia develop. Which deficiency is relevant?

Worked reasoning and transfer

Best answer: Vitamin A. Retinoids are necessary for retinal phototransduction and epithelial differentiation.

Transfer: What other ocular change may appear?

Decision 2: An adult has macrocytosis and distal vibration-sense loss. Which nutrient is concerning?

Worked reasoning and transfer

Best answer: Vitamin B12. B12 deficiency can affect DNA synthesis and myelin function.

Transfer: Why is neuro exam useful here?

Decision 3: Severe fasting intolerance causes hypoketotic hypoglycemia. Which substrate pathway warrants investigation?

Worked reasoning and transfer

Best answer: Fatty acid oxidation. Impaired fatty acid oxidation can compromise fasting energy and ketogenesis.

Transfer: What alternative hormonal cause must be considered?

Explain it back: Write a causal chain for one decision, then identify which piece of evidence would change the answer.

Unscored teaching examples; not validated assessment items or patient-specific advice.

How to use this foundation map

  1. Identify the organizing mechanism.
  2. Recognize the pattern.
  3. Restate the rule without looking.
  4. Test transfer with applications and question practice.

Pair CPR with the 5P Approach™ when solving cases and questions.